Dosing

one quick-
dissolving dose.
anytime. anywhere.1

The first and only CGRP receptor antagonist available as an ODT.1,2

CGRP: calcitonin gene-related peptide

no water necessary

No titration needed1

Can be taken up to
once daily as needed.
No water necessary.*

medication

Can be co‑administered
with oral contraceptives
and antidepressants.1,3

syringe, tablet, capsule

Studied in patients
taking preventive
medication
for migraine.1,3

Not contraindicated
in people with stable
cardiovascular disease
or risk factors.1,4

*The safety of treating more than 15 migraines in a 30-day period has not been established.1

Convenience of
one rapidly
disintegrating dose1,2

How to Take

hold pill between fingers

ready

Instruct patients to only
remove Nurtec ODT
from the blister pack
immediately before use1

No titration needed1

put pill in mouth

set

Patients can place
Nurtec ODT on or under
their tongue and it
dissolves within
seconds—no water
needed1,4

thumbs up

go

In clinical trials, some
people experienced
pain relief and returned
to normal function in
just 60 minutes with
Nurtec ODT2,6*

Nurtec ODT has
a Tmax of 1.5 hours1

In a multi-center, double-blind, randomized, placebo-controlled study of 1351 patients (Nurtec ODT 75 mg, n=669; placebo, n=682), the co-primary endpoints were freedom from pain and the absence of the most bothersome symptom (MBS) 2 hours post dose.1

*37% (n=246/669) patients experienced pain relief vs 31% (n=213/682) on placebo (P<.05).2
22% (n=149/669) patients experienced return to normal function vs 16% (n=108/682) on placebo (P=.0025).2,6

How to prescribe Nurtec ODT1

Prescribing Nurtec ODT 8-packs1

Each 8-pack of Nurtec ODT is meant to cover 8 migraine
attacks, as needed up to once daily.

Prescription: "Once daily PRN for migraine"

Dispense #8

The safety of treating more than 15 migraines in a
30-day period has not been established.

Nurtec™ ODT (rimegepant) 75 mg orally disintegrating tablets 8 pack

Additional prescribing considerations1:

Packaging: Nurtec ODT comes in 8-tablet packs

Once daily PRN: Take one 75 mg orally disintegrating tablet (ODT), as needed, for migraine

24 hour max: one 75 mg ODT

30 day max: The safety of treating more than 15 migraines in a 30 day period has not been established

Getting started with Nurtec ODT

Questions? We're here to help: Call us at 1‑833‑4NURTEC (M-F from 8 am - 8 pm ET)

Nurtec™ ODT (rimegepant) 75 mg orally disintegrating tablets starter kit

Patient Starter Kit

Each kit comes with two convenient orally disintegrating
tablets for your patients to try.

References: 1. Nurtec ODT. Package insert. Biohaven Pharmaceuticals Inc. 2. Croop R, Goadsby PJ, Stock DA, et al. Efficacy, safety, and tolerability of rimegepant orally disintegrating tablet for the acute treatment of migraine: a randomised, phase 3, double-blind, placebo-controlled trial. Lancet. 2019;394(10200):737-745. doi: 10.1016/S0140-6736(19)31606-X. 3. Data on File. RIM112. Biohaven Pharmaceuticals Inc. 4. Data on File. RIM130. Biohaven Pharmaceuticals Inc. 5. Abay FB, Ugurlu T. Orally Disintegrating Tablets: A Short Review. J Pharm Drug Devel. 2015;3(3):303-311. doi: 10.15744/2348-9782.3.303 6. Data on File. RIM107. Biohaven Pharmaceuticals Inc.

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Safety

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Savings & Support

Important Safety Information

Contraindications: Hypersensitivity to Nurtec ODT or any of its components.

Warnings and Precautions: If a serious hypersensitivity reaction occurs, discontinue Nurtec ODT and initiate appropriate therapy. Serious hypersensitivity reactions have included dyspnea and rash, and can occur days after administration.

Adverse Reactions: The most common adverse reaction was nausea (2% in patients who received Nurtec ODT compared to 0.4% in patients who received placebo). Hypersensitivity, including dyspnea and rash, occurred in less than 1% of patients treated with Nurtec ODT.

Drug Interactions: Avoid concomitant administration of Nurtec ODT with strong inhibitors of CYP3A4, strong or moderate inducers of CYP3A or inhibitors of P‑gp or BCRP. Avoid another dose of Nurtec ODT within 48 hours when it is administered with moderate inhibitors of CYP3A4.

Use in Specific Populations: Pregnant/breast feeding: It is not known if Nurtec ODT can harm an unborn baby or if it passes into breast milk. Hepatic impairment: Avoid use of Nurtec ODT in persons with severe hepatic impairment. Renal impairment: Avoid use in patients with end-stage renal disease.

Indication

Nurtec ODT is indicated for the acute treatment of migraine with or without aura in adults.

Limitations of Use
Nurtec ODT is not indicated for the preventive treatment of migraine.

Please click here for full Prescribing Information.