Why Nurtec^™ODT (rimegepant)

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Based on patient-reported insights:

For people suffering from migraine, living with trade-offs is a painful reality^1,2

For the busy professional, it can mean choosing between: Treating their migraine and missing a workday, AGAIN¹ OR Holding off treatment and having an unproductive day at the office, AGAIN¹

For the mom on-the-go, it can mean choosing between: Treating their migraine and missing out on family time because of dizziness and tiredness² OR Holding off treatment and having the pain of migraine as an unbearable distraction²

For the active multitasker, it can mean choosing between: Treating their migraine and feeling wiped out² OR Holding off treatment and fighting through every minute due to concerns about treatment side effects²

See how Nurtec ODT may help your patients dealing with trade‑offs

see efficacy

Did you know?

Over
74% of patients were not completely satisfied with their acute treatments.³

46%
of people reported that the side effects of their migraine treatments interfered with their ability to work or go to school.⁴

Based on a December 23, 2019-January 17, 2020 U.S. online survey completed by 528 adults with migraine. Respondents were recruited from the National Headache Foundation membership list.³

How Nurtec ODT works

One dose can inhibit three CGRP*-induced effects by selectively binding to CGRP receptors ^5-9

Inhibits vasodilation without active vasoconstriction

neurogenic inflammation — Inhibits neurogenic
inflammation

*Calcitonin gene-related peptide

See the Doctor Discussion Guide on Nurtec.com to find out about topics your patients may raise with you regarding their migraine experiences and treatment goals.

References: 1. Ford JH, Jackson J, Milligan G, Cotton S, Ahl J, Aurora SK. A Real-World Analysis of Migraine: A Cross-Sectional Study of Disease Burden and Treatment Patterns. Headache. 2017;57(10):1532-1544. doi: 10.1111/head.13202. 2. Data on File. RIM127. Biohaven Pharmaceuticals Inc. 3. Data on File. RIM144. Biohaven Pharmaceuticals Inc. 4. Data on File. RIM145. Biohaven Pharmaceuticals Inc. 5. Nurtec ODT. Package insert. Biohaven Pharmaceuticals Inc. 6. Durham PL. CGRP-Receptor Antagonists — A Fresh Approach to Migraine Therapy? N Engl J Med. 2004;350(11):1073-1075. doi: 10.1056/NEJMp048016. 7. Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of Migraine: A Disorder of Sensory Processing. Physiol Rev. 2017;97(2):553-622. doi: 10.1152/physrev.00034.2015. 8. Iyengar S, Johnson KW, Ossipov MH, Aurora SK. CGRP and the Trigeminal System in Migraine. Headache. 2019;59(5):659-681. doi: 10.1111/head.13529. 9. Edvinsson L, Haanes KA, Warfvinge K, Krause DN. CGRP as the target of new migraine therapies — successful translation from bench to clinic. Nat Rev Neurol. 2018 Jun;14(6):338-350. doi: 10.1038/s41582-018-0003-1.

Savings Program Terms & Conditions

To the Patient: In order to participate in the Nurtec ODT Patient Savings Program ("Program"), you must have a valid prescription for Nurtec™ ODT (rimegepant) orally disintegrating tablets, meet the eligibility requirements set forth herein, adhere to the terms and conditions stated in the Restrictions section below, and present this card to your pharmacist. Eligible patients with commercial insurance may pay as little as $0 out of pocket and limited to one 8‑tablet prescription per month. Patients with questions about the Program should call 1‑800‑761‑1568.

To the Pharmacist: By redeeming this offer, the Pharmacist certifies: (a) that the Pharmacy has not submitted, and will not submit, a claim for reimbursement under any federal, state, or other government programs for this prescription or where prohibited by law and (b) the Pharmacist will adhere to the terms and conditions stated in the Restrictions section below.

Pharmacist Instructions: For Commercially Insured Patients, please submit this claim to the patient's primary Third‑Party Payer first, then submit the balance due to CHANGE HEALTHCARE as a Secondary Payer COB (coordination of benefits) with patient responsibility and a valid Other Coverage Code (e.g. 08). Reimbursement will be received from CHANGE HEALTHCARE. For questions, please call the Concierge line for Nurtec ODT at 1‑800‑731‑4997, Monday – Friday, 8 am – 8 pm ET.

Restrictions: This offer is not valid for Non‑Insured/Cash-Paying Patients. This Program is not valid for prescriptions covered by or submitted for reimbursement in part or in full by any state or federally funded programs, including but not limited to Medicare, Medicaid, Medigap, VA, TRICARE (DOD). Patients with managed care restrictions (e.g., prior authorization, step edit) may not be eligible for this offer if such managed care restrictions persist. Continued eligibility may require that the patient has a prior authorization form submitted. This offer may not be used with any other financial assistance program, free trial, discount, prescription savings card or other offer. Valid only for patients 18 years and older in the United States including the Commonwealth of Puerto Rico. This Program is void if copied, transferred, purchased, altered, or traded and where prohibited by law. Limit one offer per individual. This offer expires on December 31, 2020. Biohaven Pharmaceuticals reserves the right to rescind, revoke or amend this offer without notice anytime. This Program is managed by ConnectiveRx on behalf of Biohaven Pharmaceuticals.

Why Nurtec^™ODT (rimegepant)

See how Nurtec ODT may help your patients dealing with trade‑offs

Did you know?

How Nurtec ODT works

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Important Safety Information

Indication

Why Nurtec™ ODT (rimegepant)

See how Nurtec ODT may help your patients dealing with trade‑offs

Did you know?

How Nurtec ODT works

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Next Page >

Important Safety Information

Indication

Why Nurtec^™ODT (rimegepant)